Endocrine Abstracts

IntroductionCardiothyreosis is associated with higher morbidity and mortality than other forms of hyperthyroidism. The aim of our study was to identify its therapeutic and evolutive aspects in an adult population of southern Tunisia.MethodsRetrospective study including all cases of cardiothyreosis followed in our department during a period of 20 years.Results100 c...

Introduction: Congenital hyperinsulinism (CHI) is a rare disease with an incidence of 1 in 30,000. It is the most common cause of persistent neonatal hypoglycemia, primarily due to inhibitory mutations in genes encoding the ATP-sensitive potassium channel in pancreatic beta cells, with ABCC8 (SUR1) and KCNJ11 (Kir6.2) mutations being the most frequent. In this context, we report a highly unusual case in terms of phenotypic and evolutionary aspects.Clinic...

Introduction: Distal and symmetrical peripheral polyneuropathy is the most frequent type of diabetic neuropathy. Its painful form (PDN) is the most common cause of non-traumatic neuropathic pain and can place a heavy burden on elderly patients’ lives. Despite the major impact that it can have on the quality of life, PDN is generally underdiagnosed because of a large interindividual variability of symptoms and in the absence of well-established diagnostic criteria.<p c...

Introduction: Mitochondrial diabetes (MD) is characterized by a wide spectrum of phenotypic and genotypic manifestations. Through a cohort study of 40 patients with MD, we attempted to establish a correlation between this diversity of phenotypic expression and the biomolecular substrate of the mitochondrial genome within the Tunisian population.Results: Epidemiologically and anthropometrically, our series aligns with literature data, with an onset age of...

Introduction: Metabolic syndrome (MS) is responsible for the increased cardiovascular risk in type 2 diabetics. There is a scarcity of research on the metabolic syndrome among individuals diagnosed with type 1 diabetes (T1DM). The aim of this study is to describe clinical, biochemical and therapeutic characteristics of T1DM with MS.Materials and Methods: Retrospective study including 36 patients, with T1DM and MS, hospitalized in the department of Endocr...

Background: To be able to manage their disease and live with it, type 2 diabetic patients need to understand and be aware of their disease. Educational diagnosis should therefore assess patients’ perception of their diabetes.Aims: This study aims to carry out a self-assessment of diabetic patients’ knowledge of their diseaseMethods: Our study is a descriptive and analytical cross-sectional study which took place during th...

Background: Low medication adherence is a frequent problem in elderly individuals with chronic diseases such as diabetes. The objective is to assess the level of medication adherence and identify predictive factors for poor adherence among elderly diabetic patients.Methods: We conducted a descriptive, cross-sectional study among diabetic patients aged 65 years and older, who were attending the Endocrinology Department at Hedi Chaker University Hospital i...

Background: Interest health applications and networks for self-management of diabetes are growing. Furthermore, the potential influence of social media on health information spread is remarkable. Aim: This study aims to determine the role of the new telecommunication technology in the dissemination of therapeutic education in our population.Methods: Our study is an descriptive and analytical cross-sectional study which took place d...

Introduction: Diabetic foot wounds (DFW) are one of the most challenging complications of diabetes. DFW is one of the leading causes of foot ulceration and amputation in patients with diabetes mellitus. Then, a multidisciplinary approach is of a great importance in the prevention and management of DFW. Healthcare personnel, particularly nurses, have an important role in this process. The objective of our study was to evaluate nurses ‘knowledge on diabetic foot wounds mana...

Introduction: Moringa is a common tropical tree in Africa that has become a subject of interest for scientists due to its interesting composition and nutritional qualities. The objective of this study was to evaluate the effects of Moringa oleifera powder on metabolic parameters in diabetic patients in the short term.Method: We conducted a randomized controlled study with ten type 2 diabetic patients treated with oral antidiabetic medications. Each patie...